Article
KNG1 Ile581Thr and susceptibility to venous thrombosis.
Blood - 31 Mar 2011
Morange Pierre-Emmanuel, Oudot-Mellakh Tiphaine, Cohen William, Germain Marine, Saut Noémie, Antoni Guillemette, Alessi Marie-Christine, Bertrand Marion, Dupuy Anne-Marie, Letenneur Luc, Lathrop Mark, Lopez Lorna M, Lambert Jean-Charles, Emmerich Joseph, Amouyel Philippe, Trégouët David-Alexandre
Abstract excerpt
Three single nucleotide polymorphisms (SNPs) were recently found to be associated with activated partial thromboplastin time (aPTT). Because shortened aPTT levels have been observed in patients experiencing venous thrombosis (VT), we investigated the effects of these 3 aPTT-associated SNPs, rs2731672, rs9898, and rs710446, on the risk of VT in a sample of 1110 healthy patients and 1542 patients with VT. Among the...
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