Article
[hTERT single nucleotide polymorphism is associated with increased risks of hepatocellular carcinoma and tumor metastasis].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Jan 2011
Dong Jin, Wang Ling, Tian Ya-ping, Guo Yue, Liu Hong-ying
Abstract excerpt
OBJECTIVE: To investigate the effect of hTERT single nucleotide polymorphisms on the development and metastasis of hepatocellular carcinoma. METHODS: A total of 290 male patients were divided into hepatitis-induced primary hepatocellular carcinoma (HCC) group (n%162), metastatic HCC group (n%22), and control group (n%106). hTERT gene was amplified and hTERT single nucleotide polymorphisms (SNPs) were tested in...
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