Article
[Retinal degeneration. Apoptosis as pathomechanism and therapy strategy].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft - 1 Mar 2001
Reichel M B, Schlichtenbrede F, Paul D, Wiedemann P
Abstract excerpt
Molecular techniques in ophthalmology and related subjects have led in recent years to the identification of many genes expressed in photoreceptor cells and have allowed the characterization of mutations leading to distinct phenotypes of retinal degeneration. Programmed cell death, or apoptosis, has been identified as the final common pathway in this disease group. A cascade of events has evolved, starting with...
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