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Article

Molecular mechanism for the antigonococcal action of lysosomal cathepsin G.

Molecular microbiology - 1 Aug 1990

Shafer W M, Onunka V C, Jannoun M, Huthwaite L W

Abstract excerpt

Human lysosomal cathepsin G (cat G) appears to be an important mediator of non-oxidative killing of Neisseria gonorrhoeae ingested by human polymorphonuclear leucocytes (PMNLs). Nearly isogenic strains of gonococci having variations in the structure of penicillin-binding protein 2 (PBP2) also exh...

Topics

Animals
Bacterial Proteins
Base Sequence
Carrier Proteins
Cathepsin G
Cathepsins
Cloning, Molecular
Densitometry
Genes, Bacterial
Hexosyltransferases
Humans
Lysosomes
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multienzyme Complexes

Muramoylpentapeptide Carboxypeptidase

Mutation

Neisseria gonorrhoeae

Neutrophils

Source

Identifiers

PMID: 2126324
DOI: 10.1111/j.1365-2958.1990.tb00706.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2126324-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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