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Article

Molecular mechanism for the antigonococcal action of lysosomal cathepsin G.

Molecular microbiology - 1 Aug 1990

Shafer W M, Onunka V C, Jannoun M, Huthwaite L W

Abstract excerpt

Human lysosomal cathepsin G (cat G) appears to be an important mediator of non-oxidative killing of Neisseria gonorrhoeae ingested by human polymorphonuclear leucocytes (PMNLs). Nearly isogenic strains of gonococci having variations in the structure of penicillin-binding protein 2 (PBP2) also exhibit different levels of susceptibility to the lethal action of cat G in vitro. Accordingly, we examined the...

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Identifiers

PMID: 2126324
DOI: 10.1111/j.1365-2958.1990.tb00706.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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