Neisseria gonorrhoeae Metalloprotease NGO1686 Is Required for Full Piliation, and Piliation Is Required for Resistance to H 2 O 2 - and Neutrophil-Mediated Killing

doi:10.1128/mbio.00399-13

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Neisseria gonorrhoeae Metalloprotease NGO1686 Is Required for Full Piliation, and Piliation Is Required for Resistance to H 2 O 2 - and Neutrophil-Mediated Killing

10 Jul 2013

Abstract excerpt

UNLABELLED: The sexually transmitted infection gonorrhea is caused exclusively by the human-specific pathogen Neisseria gonorrhoeae. Type IV pili are an essential virulence factor uniformly expressed on clinical gonococcal isolates and are required for several aspects of gonococcal pathogenesis, including adherence to host tissues, autoagglutination, twitching motility, and the uptake of DNA during...

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PMID: 23839218
DOI: 10.1128/mbio.00399-13

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