Article
Artificial compounds differentially control Dictyostelium chemotaxis and cell differentiation.
Cell structure and function - 1 Jan 2011
Kuwayama Hidekazu, Kikuchi Haruhisa, Oshima Yoshiteru, Kubohara Yuzuru
Abstract excerpt
Differentiation-inducing factor-1 and -2 (DIF-1 and DIF-2) are small lipophilic signal molecules that control both cell differentiation and chemotaxis in the cellular slime mold Dictyostelium discoideum. In this study, we examined the effects of four amide derivatives of DIF-1 on stalk cell differentiation and chemotaxis. The DIF derivatives differentially affected cell differentiation and chemotaxis, suggesting...
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