Article
A genome-wide scan in affected sibling pairs with idiopathic recurrent miscarriage suggests genetic linkage.
Molecular human reproduction - 1 Jun 2011
Kolte A M, Nielsen H S, Moltke I, Degn B, Pedersen B, Sunde L, Nielsen F C, Christiansen O B
Abstract excerpt
Previously, siblings of patients with idiopathic recurrent miscarriage (IRM) have been shown to have a higher risk of miscarriage. This study comprises two parts: (i) an epidemiological part, in which we introduce data on the frequency of miscarriage among 268 siblings of 244 patients with IRM and (ii) a genetic part presenting data from a genome-wide linkage study of 38 affected sibling pairs with IRM. All IRM...
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