Article
Increased prevalence of the Plasmodium falciparum Pfmdr1 86N genotype among field isolates from Franceville, Gabon after replacement of chloroquine by artemether-lumefantrine and artesunate-mefloquine.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2011
Lekana-Douki Jean Bernard, Dinzouna Boutamba Sylvatrie Danne, Zatra Rafika, Zang Edou Sonya Estelle, Ekomy Hervé, Bisvigou Ulrick, Toure-Ndouo Fousseyni S
Abstract excerpt
Despite global antimalarial measures, Plasmodium falciparum malaria remains a major public health problem. WHO has recommended the use of arteminisin-based combination therapy to limit the emergence of antimalarial drug resistance. However, ACT treatment failures have been linked to the selection...
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