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Article

EMT is the dominant program in human colon cancer

20 Jan 2011

Abstract excerpt

BACKGROUND: Colon cancer has been classically described by clinicopathologic features that permit the prediction of outcome only after surgical resection and staging. METHODS: We performed an unsupervised analysis of microarray data from 326 colon cancers to identify the first principal component (PC1) of the most variable set of genes. PC1 deciphered two primary, intrinsic molecular subtypes of colon cancer that...

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PMID: 21251323
DOI: 10.1186/1755-8794-4-9

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