Article
Cytochrome P450 3A activity in mothers and their neonates as determined by plasma 4β-hydroxycholesterol.
European journal of clinical pharmacology - 1 Jul 2011
Nylén Hanna, Sergel Sofia, Forsberg Lisa, Lindemalm Synnöve, Bertilsson Leif, Wide Katarina, Diczfalusy Ulf
Abstract excerpt
PURPOSE: The purpose of this study was to determine the 4β-hydroxycholesterol to cholesterol ratio in mothers and neonates at the time of birth and 4 months post-partum. METHOD: 21 mothers and 22 neonates were recruited at the delivery ward at Karolinska University Hospital, Huddinge, Sweden. Blood samples taken from mothers and neonates at birth and 4 months post-partum were analysed for 4β-hydroxycholesterol...
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