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Article

New prognostic markers in acute myeloid leukemia: perspective from the clinic.

Hematology. American Society of Hematology. Education Program - 1 Jan 2010

Foran James M

Abstract excerpt

Acute myeloid leukemia (AML) is a disease with marked heterogeneity in both response to therapy and survival. Cytogenetics, age, and performance status have long determined prognosis and therapy. The advent of molecular diagnostics has heralded an explosion in new prognostic factors, including gene mutations in KIT, FLT3 (Fms-like tyrosine kinase 3), NPM1 (nucleophosmin 1), and CEBPA (CCAAT enhancer-binding...

Topics

Animals
Biomarkers, Tumor
DNA Methylation
Humans
Leukemia, Myeloid, Acute
Mutation
Nucleophosmin
Polymorphism, Single Nucleotide
Prognosis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21239770
DOI: 10.1182/asheducation-2010.1.47

Genes

FLT3
KIT
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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