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Article

GCKR mutations in Japanese families with clustered type 2 diabetes.

Molecular genetics and metabolism - 1 Apr 2011

Tanaka Daisuke, Nagashima Kazuaki, Sasaki Mayumi, Yamada Chizumi, Funakoshi Shogo, Akitomo Kimiyo, Takenaka Katsunobu, Harada Kouji, Koizumi Akio, Inagaki Nobuya

Abstract excerpt

OBJECTIVE: The aim was to investigate the genetic background of familial clustering of type 2 diabetes. SUBJECTS AND METHODS: We recruited Japanese families with a 3-generation history of diabetes. Genome-wide linkage analysis was performed assuming an autosomal dominant model. Genes in the linkage region were computationally prioritized using Endeavour. We sequenced the candidate genes, and the frequencies of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

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Share to Mutation, Missense

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Source

Identifiers

PMID: 21236713
DOI: 10.1016/j.ymgme.2010.12.009

Genes

GCKR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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