Article
IgD-receptor-positive human T lymphocytes. I. Modulation of receptor expression by oligomeric IgD and lymphokines.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1990
Coico R F, Tamma S L, Bessler M, Wei C F, Thorbecke G J
Abstract excerpt
Studies with human myeloma-derived IgD have demonstrated the existence of IgD-R on peripheral blood T cells. These receptors, which are detected by rosetting with IgD-coated ox E (IgD-rosette-forming cells), are competitively inhibited by IgD, but not by IgM or IgG. Similar results were obtained...
Topics
- Antigens, Differentiation, T-Lymphocyte
- CD4 Antigens
- CD8 Antigens
- Cell Line
- Humans
- Immunoglobulin D
- Lymphocyte Activation
- Lymphokines
- Phenotype
- Receptors, Fc
- Receptors, Immunologic
- Rosette Formation
- T-Lymphocytes
- Up-Regulation
