Article
An application of the elastic net for an endophenotype analysis.
Behavior genetics - 1 Jan 2011
Palejev Dean, Hwang Wookyeon, Landi Nicole, Eastman Maria, Frost Stephen J, Fulbright Robert K, Kidd Judith R, Kidd Kenneth K, Mason Graeme F, Mencl W Einar, Yrigollen Carolyn, Pugh Kenneth R, Grigorenko Elena L
Abstract excerpt
We provide an illustration of an application of the elastic net to a large number of common genetic variants in the context of the search for the genetic bases of an endophenotype conceivably related to individual differences in learning. GABA concentration in the occipital cortex, a critical area for reading, was obtained in a group (n = 76) of children aged 6-10 years. Two extreme groups, high and low, were...
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