Article
Bronchioloalveolar neoplasia.
International journal of clinical and experimental pathology - 12 Nov 2010
Kitamura Hitoshi, Okudela Koji
Abstract excerpt
Bronchioloalveolar carcinoma (BAC) arising in the peripheral lung is the prototype of human lung adenocar-cinoma and is considered to develop, at least in part, from its precursor atypical adenomatous hyperplasia (AAH). Molecular genetics investigations have revealed the significant roles of mutations in KRAS and epidermal growth factor receptor (EGFR) genes in the pathogenesis of AAH and BAC. Recently, selective...
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