Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

On the robustness of tests of genetic associations incorporating gene-environment interaction when the environmental exposure is misspecified.

Epidemiology (Cambridge, Mass.) - 1 Mar 2011

Tchetgen Tchetgen Eric J, Kraft Peter

Abstract excerpt

We consider the robustness of tests of genetic associations that incorporate gene-environment interactions when the environmental exposure is misspecified, which is likely the case when the exposure is continuous. We formally prove that, under the null hypothesis of no genetic association, misspe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Environmental Exposure
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Likelihood Functions

Share to Logistic Models

Share to Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 21228699
DOI: 10.1097/EDE.0b013e31820877c5
PMCID: PMC5972372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21228699-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

On the robustness of tests of genetic associations incorporating gene-environment interaction when the environmental exposure is misspecified.PMID 21228699Read ↗

On the interpretation, robustness, and power of varieties of case-only tests of gene-environment interaction.Semantic proximity Read ↗

Gene-environment interactions in case-control studies with silent disease.Semantic proximity Read ↗

Robustness of inference on measured covariates to misspecification of genetic random effects in family studies.Semantic proximity Read ↗

The impact of imprecisely measured covariates on estimating gene-environment interactions.Semantic proximity Read ↗

Impact of population substructure on trend tests for genetic case-control association studies.Semantic proximity Read ↗

The virtues of a deliberately mis-specified disease model in demonstrating a gene-environment interaction.Semantic proximity Read ↗

Genetic association tests in the presence of epistasis or gene-environment interaction.Semantic proximity Read ↗

Robust discovery of genetic associations incorporating gene-environment interaction and independence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.