Article
Polymorphisms of cyclo-oxygenases and 5-lipo-oxygenase-activating protein are associated with chronic spontaneous urticaria and urinary leukotriene E4.
European journal of dermatology : EJD - 1 Jan 2000
Di Lorenzo Gabriele, Pacor Maria Luisa, Candore Giuseppina, Listi Florinda, Ditta Vito, Leto-Barone Maria Stefania, D'Alcamo Alberto, Martinelli Nicola, Corrocher Roberto, Caruso Calogero
Abstract excerpt
The mechanisms of chronic spontaneous urticaria (CSU) continue to be unknown. Our working hypothesis is that polymorphisms of cyclo-oxygenases and 5-lipo-oxygenase-activating protein may be involved in the pathways leading to CSU. We examined five candidate polymorphisms of cyclo-oxygenases 1 and 2 and of 5-lipo-oxygenase-activating protein in 109 controls and in 94 CSU patients from Northern Italy. We also...
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