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Article

Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study.

BMC medical genomics - 11 Jan 2011

Wineinger Nathan E, Patki Amit, Meyers Kristin J, Broeckel Ulrich, Gu Charles C, Rao D C, Devereux Richard B, Arnett Donna K, Tiwari Hemant K

Abstract excerpt

BACKGROUND: Aortic root diameter is a clinically relevant trait due to its known relationship with the pathogenesis of aortic regurgitation and risk for aortic dissection. African Americans are an understudied population despite a particularly high burden of cardiovascular diseases. We report a genome-wide association study on aortic root diameter among African Americans enrolled in the HyperGEN study. We invoked...

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Identifiers

PMID: 21223598
DOI: 10.1186/1755-8794-4-4
PMCID: PMC3027088

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CRCP
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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