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Article

The genetic component of bicuspid aortic valve and aortic dilation. An exome-wide association study.

Journal of molecular and cellular cardiology - 1 Jan 2017

Gago-Díaz Marina, Brion María, Gallego Pastora, Calvo Francisco, Robledo-Carmona Juan, Saura Daniel, Sánchez Violeta, Bermejo Javier, Sevilla Teresa, Newton-Cheh Christopher, Carracedo Ángel, Muehlschlegel J Daniel, García-Dorado David, Body Simon C, Evangelista Artur

Abstract excerpt

BACKGROUND: Bicuspid aortic valve is the most common cardiovascular congenital malformation affecting 2% of the general population. The incidence of life-threatening complications, the high heritability, and familial clustering rates support the interest in identifying risk or protective genetic factors. The main objective of the present study was to identify population-based genetic variation associated with...

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Identifiers

PMID: 27894865
DOI: 10.1016/j.yjmcc.2016.11.012

Genes

HMCN2

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