Article
Construction and characterisation of a Yersinia enterocolitica O:8 ompR mutant.
FEMS microbiology letters - 1 Aug 1998
Dorrell N, Li S R, Everest P H, Dougan G, Wren B W
Abstract excerpt
The ompR-envZ two-component regulatory system has been shown to contribute to virulence in a number of enteric bacterial pathogens. A Yersinia enterocolitica O:8 ompR homologue was amplified, cloned and sequenced, showing 99.2% homology to the Escherichia coli OmpR. An isogenic ompR mutant was co...
Topics
- Animals
- Bacterial Proteins
- Base Sequence
- Cloning, Molecular
- Colony Count, Microbial
- Genes, Regulator
- Hydrogen-Ion Concentration
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
- Osmolar Concentration
- Polymerase Chain Reaction
- Temperature
- Trans-Activators
- Virulence
- Yersinia enterocolitica