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Article

High epidermal growth factor receptor amplification rate but low mutation frequency in Middle East lung cancer population.

Human pathology - 1 Apr 2006

Al-Kuraya Khawla, Siraj Abdul K, Bavi Prashant, Al-Jommah Naif, Ezzat Adnan, Sheikh Salwa, Amr Samir, Al-Dayel Fouad, Simon Ronald, Guido Sauter

Abstract excerpt

Epidermal growth factor receptor (EGFR) exon 18-21 mutations were shown to be highly predictive of response to gefitinib (Iressa) therapy in lung cancer. Studies on Western and Japanese lung cancers have indicated substantial differences in the EGFR mutation frequency between these populations. To investigate the prevalence of EGFR in another distinct ethnic group, EGFR alterations were studied in 47 consecutive...

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Source

Identifiers

PMID: 16564920
DOI: 10.1016/j.humpath.2005.12.004

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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