Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells

9 Jan 2011

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma has a high mortality rate due to its rate of recurrence. Acyclic retinoid prevents recurrence of hepatocellular carcinoma in patients after surgical removal of their primary tumors by inducing apoptosis in hepatocellular carcinoma cells, although the molecular mechanisms of action are not understood. METHODS: Human hepatocellular carcinoma cells in culture, as well as nude...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood properties and coagulation
Share to Cell death mechanisms and regulation
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21214951
DOI: 10.1186/1476-4598-10-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cellsPMID 21214951Read ↗

Synergistic induction of apoptosis by acyclic retinoid and interferon-β in human hepatocellular carcinoma cellsSemantic proximity Read ↗

6-Gingerol inhibition of inflammation and apoptosis through the activation of SIRT1 in Balb/c miceSemantic proximity Read ↗

Acyclic retinoid inhibits human hepatoma cell growth by suppressing fibroblast growth factor-mediated signaling pathwaysSemantic proximity Read ↗

Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κBSemantic proximity Read ↗

REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancerSemantic proximity Read ↗

Prevention of Second Primary Tumors by an Acyclic Retinoid in Patients with Hepatocellular CarcinomaSemantic proximity Read ↗

Silencing glypican-3 expression induces apoptosis in human hepatocellular carcinoma cellsSemantic proximity Read ↗

Promising Gene Therapy Using an Adenovirus Vector Carrying REIC/Dkk-3 Gene for the Treatment of Biliary CancerSemantic proximity Read ↗

Growth inhibition of human hepatocellular carcinoma cells by overexpression of G-protein-coupled receptor kinase 2.Semantic proximity Read ↗

Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.Semantic proximity Read ↗

Trans-splicing repair of mutant p53 suppresses the growth of hepatocellular carcinoma cells in vitro and in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.