Article
Bacteria-based AND logic gate: a decision-making and self-powered biosensor.
Chemical communications (Cambridge, England) - 21 Mar 2011
Li Zhongjian, Rosenbaum Miriam A, Venkataraman Arvind, Tam Tsz Kin, Katz Evgeny, Angenent Largus T
Abstract excerpt
We developed a bacteria-based AND logic gate using a Pseudomonas aeruginosa lasI/rhlI double mutant with two quorum-sensing signaling molecules as the input signals. We showed a distinct electrical output signal, despite the complexity and continuous regulation of metabolic reactions of living cells.
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