Article
Natural type 3/type 2 intertypic vaccine-related poliovirus recombinants with the first crossover sites within the VP1 capsid coding region.
PloS one - 21 Dec 2010
Zhang Yong, Zhu Shuangli, Yan Dongmei, Liu Guiyan, Bai Ruyin, Wang Dongyan, Chen Li, Zhu Hui, An Hongqiu, Kew Olen, Xu Wenbo
Abstract excerpt
BACKGROUND: Ten uncommon natural type 3/type 2 intertypic poliovirus recombinants were isolated from stool specimens from nine acute flaccid paralysis case patients and one healthy vaccinee in China from 2001 to 2008. PRINCIPAL FINDINGS: Complete genomic sequences revealed their vaccine-related g...
Topics
- Antigens
- Base Sequence
- Capsid Proteins
- China
- Genome, Viral
- Genotype
- Humans
- Molecular Sequence Data
- Muscle Hypotonia
- Nucleotides
- Paralysis
- Phenotype
- Poliovirus Vaccine, Oral
- Sequence Homology, Nucleic Acid