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Article

Natural type 3/type 2 intertypic vaccine-related poliovirus recombinants with the first crossover sites within the VP1 capsid coding region.

PloS one - 21 Dec 2010

Zhang Yong, Zhu Shuangli, Yan Dongmei, Liu Guiyan, Bai Ruyin, Wang Dongyan, Chen Li, Zhu Hui, An Hongqiu, Kew Olen, Xu Wenbo

Abstract excerpt

BACKGROUND: Ten uncommon natural type 3/type 2 intertypic poliovirus recombinants were isolated from stool specimens from nine acute flaccid paralysis case patients and one healthy vaccinee in China from 2001 to 2008. PRINCIPAL FINDINGS: Complete genomic sequences revealed their vaccine-related genomic features and showed that their first crossover sites were randomly distributed in the 3' end of the VP1 coding...

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PMID: 21203565
DOI: 10.1371/journal.pone.0015300
PMCID: PMC3006203

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