Article
TbUNC119 and its binding protein complex are essential for propagation, motility, and morphogenesis of Trypanosoma brucei procyclic form cells.
PloS one - 22 Dec 2010
Ohshima Shigeru, Ohashi-Suzuki Mitsuko, Miura Yutaka, Yabu Yoshisada, Okada Noriko, Ohta Nobuo, Suzuki Takashi
Abstract excerpt
Flagellum-mediated motility of Trypanosoma brucei is considered to be essential for the parasite to complete stage development in the tsetse fly vector, while the mechanism by which flagellum-mediated motility is controlled are not fully understood. We thus compared T. brucei whole gene products (amino acid sequence) with Caenorhabditis elegans UNC (uncoordinated) proteins, in order to find uncharacterized...
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