A functional polymorphism in the CYP3A4 gene is associated with increased risk of coronary heart disease in the Chinese Han population.

doi:10.1111/j.1742-7843.2010.00657.x

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A functional polymorphism in the CYP3A4 gene is associated with increased risk of coronary heart disease in the Chinese Han population.

Basic & clinical pharmacology & toxicology - 1 Mar 2011

He Bao-xia, Shi Lei, Qiu Jian, Tao Liang, Li Rui, Yang Liang, Zhao Shu-jin

Abstract excerpt

CYP3A4 is a major member of the cytochrome P450 (CYP) enzymes which play crucial roles in cardiovascular diseases. Recently, a novel polymorphism in the CYP3A4 gene, IVS10+12G>A, named CYP3A4*1G (rs2242480), has been identified. The aim of this study was to evaluate the potential relationship bet...

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PMID: 21199372
DOI: 10.1111/j.1742-7843.2010.00657.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21199372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

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