Ectonucleotide pyrophosphatase/phosphodiesterase 1 K173Q polymorphism is associated with diabetic nephropathy in the Taiwanese population.

doi:10.1089/gtmb.2010.0148

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Ectonucleotide pyrophosphatase/phosphodiesterase 1 K173Q polymorphism is associated with diabetic nephropathy in the Taiwanese population.

Genetic testing and molecular biomarkers - 1 Apr 2011

Lin Cheng-Chia, Wu Chun-Te, Wu Lawrence Shih-Hsin

Abstract excerpt

Diabetic nephropathy is the leading cause of end-stage renal disease in the world. The cause of diabetic nephropathy seems to be multifactorial, and about one-third of patients with diabetes eventually develop this complication. The gene encoding ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is a candidate susceptibility gene for obesity and type 2 diabetes. We assessed rs1044498 (K173Q) located in...

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PMID: 21198320
DOI: 10.1089/gtmb.2010.0148

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ENPP1

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