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Article

Mutations in the E2-PePHD region of hepatitis C virus genotype-3a and correlation with response to interferon and ribavirin combination therapy in Pakistani patients.

Virology journal - 31 Dec 2010

Afzal Samia, Idrees Muhammad, Akram Madiha, Awan Zunaira, Khubaib Bushra, Aftab Mahwish, Fatima Zareen, Badar Sadaf, Hussain Abrar

Abstract excerpt

Hepatitis C is a major health problem affecting more than 200 million individuals in the world. Current treatment regimen consisting of interferon alpha and ribavirin does not always succeed in eliminating the virus completely from patient's body. One of the mechanisms by which virus evades the antiviral effect of interferon alpha involves protein kinase (PKR) eukaryotic initiation factor 2 alpha (eIF2a)...

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Source

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Identifiers

PMID: 21194456
DOI: 10.1186/1743-422X-7-377
PMCID: PMC3019161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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