Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation of NDRG2 and c-Myc expression in rat heart during the acute stage of ischemia/reperfusion injury.

Histochemistry and cell biology - 1 Jan 2011

Sun Zhongchan, Shen Lan, Sun Xiang, Tong Guang, Sun Dongdong, Han Tenglong, Yang Guodong, Zhang Jian, Cao Feng, Yao Libo, Wang Haichang

Abstract excerpt

N-Myc downstream regulated gene 2 (NDRG2), a Myc-repressed gene, is highly expressed in heart tissue. NDRG2 increases in response to hypoxia-induced stress and is involved in hypoxia-induced radioresistance. However, little is known about the expression changes and possible roles of NDRG2 in the heart under hypoxia condition. Here, the authors show that NDRG2, mainly localized in cardiomyocyte cytoplasm, was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Blotting, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, myc

Share to Myocardial Reperfusion Injury

Share to Myocytes, Cardiac

Share to Nerve Tissue Proteins

Share to Rats, Sprague-Dawley

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 21193923
DOI: 10.1007/s00418-010-0776-9

Genes

NDRG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation of NDRG2 and c-Myc expression in rat heart during the acute stage of ischemia/reperfusion injury.PMID 21193923Read ↗

N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor SuppressorSemantic proximity Read ↗

&lt;italic&gt;NDRG2&lt;/italic&gt;: a Myc-repressed gene involved in cancer and cell stressSemantic proximity Read ↗

Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancerSemantic proximity Read ↗

EGR2 is a hub-gene in myocardial infarction and aggravates inflammation and apoptosis in hypoxia-induced cardiomyocytesSemantic proximity Read ↗

Dexmedetomidine attenuates the injury of H9C2 cardiomyocytes under Hypoxia/reoxygenation condition partly through the inhibition of endoplasmic reticulum stressSemantic proximity Read ↗

Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injurySemantic proximity Read ↗

Bioinformatic Analysis of the Protective Effects of Dexmedetomidine and Thrombopoietin against Hypoxia/Reoxygenation-Induced Injury in AC16 CellsSemantic proximity Read ↗

The Serum of MEF2D Expression in Patients with Myocardial Infarction, May be Clinical Indicators and it Mediated ROS Signaling by HDAC5Semantic proximity Read ↗

Downregulation of UQCRC1 exacerbates hypoxia-induced mitochondrial damage in H9C2 cardiomyocytesSemantic proximity Read ↗

Oxygen-dependent regulation of NDRG1 in human glioblastoma cells in vitro and in vivoSemantic proximity Read ↗

NDRG1 Targets TAF15 to Promote Endothelial Dysfunction and Hypoxia-Induced Pulmonary HypertensionSemantic proximity Read ↗

NDRG1, a growth and cancer related gene: regulation of gene expression and function in normal and disease statesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.