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Respiratory Syncytial Virus Represses Glucocorticoid Receptor-Mediated Gene Activation

29 Dec 2010

Abstract excerpt

Respiratory syncytial virus (RSV) is a common cause of bronchiolitis in infants. Although antiinflammatory in nature, glucocorticoids have been shown to be ineffective in the treatment of RSV-induced bronchiolitis and wheezing. In addition, the effectiveness of glucocorticoids at inhibiting RSV-induced proinflammatory cytokine production in cell culture has been questioned. In this study, we have investigated the...

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PMID: 21190962
DOI: 10.1210/en.2010-0774

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