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Article

Acute induction of autophagy as a novel strategy for cardioprotection: getting to the heart of the matter.

Autophagy - 1 Apr 2011

Przyklenk Karin, Undyala Vishnu Vardhan Reddy, Wider Joseph, Sala-Mercado Javier A, Gottlieb Roberta A, Mentzer Robert M

Abstract excerpt

There is no question that necrosis and apoptosis contribute to cardiomyocyte death in the setting of myocardial ischemia-reperfusion. Indeed, considerable effort and resources have been invested in the development of novel therapies aimed at attenuating necrotic and apoptotic cell death, with the ultimate goal of applying these strategies to reduce infarct size and improve outcome in patients suffering acute...

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PMID: 21187719
DOI: 10.4161/auto.7.4.14395
PMCID: PMC3679089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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