Article
Noise-induced changes in gene expression in the cochleae of mice differing in their susceptibility to noise damage.
Hearing research - 1 Jul 2011
Gratton Michael Anne, Eleftheriadou Anna, Garcia Jerel, Verduzco Esteban, Martin Glen K, Lonsbury-Martin Brenda L, Vázquez Ana E
Abstract excerpt
The molecular mechanisms underlying the vast differences between individuals in their susceptibility to noise-induced hearing loss (NIHL) are unknown. The present study demonstrated that the effects of noise over-exposure on the expression of molecules likely to be important in the development of NIHL differ among inbred mouse strains having distinct susceptibilities to NIHL including B6 (B6.CAST) and 129...
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