Article
Quantitative measure of genetic differences in susceptibility to noise-induced hearing loss in two strains of mice.
Hearing research - 1 Aug 1999
Davis R R, Cheever M L, Krieg E F, Erway L C
Abstract excerpt
The CBA/CaJ (CB) and C57BL/6J (B6) inbred strains of mice were exposed for 1 h to noise intensities between 98 and 119 dB SPL. Previous studies indicated that the B6 mice exhibited permanent threshold shifts (PTS) after 1h exposure to 110 dB, whereas the CB mice did not exhibit any PTS. These differences in susceptibility to noise-induced hearing loss (NIHL) appear to be due to a gene for age-related hearing loss...
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