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Article

The chromosomal mazEF locus of Streptococcus mutans encodes a functional type II toxin-antitoxin addiction system.

Journal of bacteriology - 1 Mar 2011

Syed Mohammad Adnan, Koyanagi Stephanie, Sharma Eesha, Jobin Marie-Claude, Yakunin Alexander F, Lévesque Céline M

Abstract excerpt

Type II chromosomal toxin-antitoxin (TA) modules consist of a pair of genes that encode two components: a stable toxin and a labile antitoxin interfering with the lethal action of the toxin through protein complex formation. Bioinformatic analysis of Streptococcus mutans UA159 genome identified a pair of linked genes encoding a MazEF-like TA. Our results show that S. mutans mazEF genes form a bicistronic operon...

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Identifiers

PMID: 21183668
DOI: 10.1128/JB.01114-10
PMCID: PMC3067577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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