Article
Associations between DRDs and schizophrenia in a Korean population: multi-stage association analyses.
Experimental & molecular medicine - 31 Jan 2011
Lee Kyu Young, Joo Eun-Jeong, Ji Yong Ick, Kim Duk-Hwan, Park Joo Bae, Chung In-Won, Lee Sang Ick, Joo Yeon Ho, Ahn Yong Min, Song Joo Yun, Kim Yong Sik
Abstract excerpt
The dysregulation of the dopaminergic system has been implicated in the pathophysiology of major psychosis, including schizophrenia, with dopamine receptor genes (DRDs) presently targeted as the most promising candidate genes. We investigated DRD1-5 for association with schizophrenia using a multi-stage approach in a Korean sample. One hundred forty-two SNPs in DRD1-5 were selected from the dbSNP, and the...
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