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Article

HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells.

The Journal of experimental medicine - 1 Sept 1990

Herman A, Croteau G, Sekaly R P, Kappler J, Marrack P

Abstract excerpt

Staphylococcal enterotoxins (SEs) have been shown to bind to major histocompatibility complex (MHC) class II proteins and stimulate T cells in a V beta-specific manner, and these V beta specificities for various SEs have been well documented in mice and humans. This study was undertaken in order to examine the ability of human class II molecules to present SEs to human and murine T cell hybridomas. Using a panel...

Topics

Alleles
Animals
Cell Line
Enterotoxins
Genes, MHC Class II
HLA-DR Antigens
Histocompatibility Antigens Class II
Humans
Mice
Staphylococcus
T-Lymphocytes

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Identifiers

PMID: 2117633
DOI: 10.1084/jem.172.3.709
PMCID: PMC2188560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2117633-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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