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Article

Analysis of ultra low genome conservation in Clostridium difficile.

PloS one - 8 Dec 2010

Scaria Joy, Ponnala Lalit, Janvilisri Tavan, Yan Weiwei, Mueller Lukas A, Chang Yung-Fu

Abstract excerpt

Microarray-based comparative genome hybridisations (CGH) and genome sequencing of Clostridium difficile isolates have shown that the genomes of this species are highly variable. To further characterize their genome variation, we employed integration of data from CGH, genome sequencing and putative cellular pathways. Transcontinental strain comparison using CGH data confirmed the emergence of a human-specific...

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Identifiers

PMID: 21170335
DOI: 10.1371/journal.pone.0015147
PMCID: PMC2999544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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