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Article

Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways.

Biological psychiatry - 15 Mar 2011

Muiños-Gimeno Margarita, Espinosa-Parrilla Yolanda, Guidi Monica, Kagerbauer Birgit, Sipilä Tessa, Maron Eduard, Pettai Kristi, Kananen Laura, Navinés Ricard, Martín-Santos Rocío, Gratacòs Mònica, Metspalu Andres, Hovatta Iiris, Estivill Xavier

Abstract excerpt

BACKGROUND: The involvement of microRNAs (miRNAs) in neuronal differentiation and synaptic plasticity suggests a role for miRNAs in psychiatric disorders; association analyses and functional approaches were used to evaluate the implication of miRNAs in the susceptibility for panic disorder. METHODS: Case-control studies for 712 single-nucleotide polymorphisms (SNPs) tagging 325 human miRNA regions were performed...

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Source

Identifiers

PMID: 21168126
DOI: 10.1016/j.biopsych.2010.10.010

Genes

BDNF
CCKBR
GABRA6
MAOA
POMC
RGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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