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Article

The role of DYRK1A in neurodegenerative diseases

11 Nov 2010

Abstract excerpt

Recent studies indicate that the dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) gene, which is located on chromosome 21q22.2 and is overexpressed in Down syndrome (DS), may play a significant role in developmental brain defects and in early onset neurodegeneration, neuronal loss and dementia in DS. The identification of hundreds of genes deregulated by DYRK1A overexpression and numerous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21156028
DOI: 10.1111/j.1742-4658.2010.07955.x

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The role of DYRK1A in neurodegenerative diseasesPMID 21156028Read ↗

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