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Article

Impact of KRAS mutation and PTEN expression on cetuximab-treated colorectal cancer.

World journal of gastroenterology - 14 Dec 2010

Li Fang-Hua, Shen Lin, Li Zhuang-Hua, Luo Hui-Yan, Qiu Miao-Zhen, Zhang Hui-Zhong, Li Yu-Hong, Xu Rui-Hua

Abstract excerpt

AIM: To investigate the prognostic value of KRAS mutation, and phosphatase and tensin (PTEN) expression in Chinese metastatic colorectal cancer metastatic colorectal cancer (mCRC) patients treated with cetuximab. METHODS: Ninety Chinese mCRC patients treated with cetuximab were evaluated for KRAS mutation and PTEN protein expression by DNA sequencing of codons 12 and 13 and immunohistochemistry, respectively. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21155011
DOI: 10.3748/wjg.v16.i46.5881
PMCID: PMC3001981

Genes

KRAS
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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