Article
Tumor necrosis factor-α: investigation of gene polymorphism and regulation of TACE-TNF-α system in patients with acute myocardial infarction.
Molecular biology reports - 1 Nov 2011
Ghaderian Sayyed Mohammad Hossein, Akbarzadeh Najar Reza, Tabatabaei Panah Akram Sadat
Abstract excerpt
A polymorphism within tumor necrosis factor-α (TNF-α) gene promoter and contribution of TNF-α converting enzyme (TACE) have been reported to be associated with TNF-α production which may increase susceptibility to heart failure such as acute myocardial infarction (AMI). However, the relationship between this polymorphism and susceptibility to AMI and the mechanism of TACE-TNF-α system regulation has poorly been...
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