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Article

The (AAT)n repeat of the cannabinoid CB1 receptor gene influences disease progression in relapsing multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Mar 2011

Rossi Silvia, Buttari Fabio, Studer Valeria, Motta Caterina, Gravina Paolo, Castelli Maura, Mantovani Vilma, De Chiara Valentina, Musella Alessandra, Fiore Stefania, Masini Silvia, Bernardi Giorgio, Maccarrone Mauro, Bernardini Sergio, Centonze Diego

Abstract excerpt

BACKGROUND: Genetic and pharmacological inactivation of cannabinoid CB(1) receptors (CB(1)Rs) exacerbates disease course in experimental autoimmune encephalomyelitis, suggesting that CB(1)Rs might play a role in the neurodegenerative damage associated with multiple sclerosis (MS). OBJECTIVES: To...

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Source

Identifiers

PMID: 21148019
DOI: 10.1177/1352458510388680

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21148019-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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