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Article

Electron cryomicroscopy structure of a membrane-anchored mitochondrial AAA protease.

The Journal of biological chemistry - 11 Feb 2011

Lee Sukyeong, Augustin Steffen, Tatsuta Takashi, Gerdes Florian, Langer Thomas, Tsai Francis T F

Abstract excerpt

FtsH-related AAA proteases are conserved membrane-anchored, ATP-dependent molecular machines, which mediate the processing and turnover of soluble and membrane-embedded proteins in eubacteria, mitochondria, and chloroplasts. Homo- and hetero-oligomeric proteolytic complexes exist, which are composed of homologous subunits harboring an ATPase domain of the AAA family and an H41 metallopeptidase domain. Mutations...

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Identifiers

PMID: 21147776
DOI: 10.1074/jbc.M110.158741
PMCID: PMC3039362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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