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Article

Human VAPA and the yeast VAP Scs2p with an altered proline distribution can phenocopy amyotrophic lateral sclerosis-associated VAPB(P56S).

Biochemical and biophysical research communications - 14 Jan 2011

Nakamichi Shoko, Yamanaka Kumiko, Suzuki Mai, Watanabe Toshio, Kagiwada Satoshi

Abstract excerpt

A human isoform of the vesicle-associated membrane protein-associated proteins (VAPs), VAPB, causes amyotrophic lateral sclerosis eight due to the missense mutation of Pro-56, whereas human VAPA and the yeast VAP Scs2p proteins are not significantly affected by similar mutations. We have found th...

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Source

Identifiers

PMID: 21144830
DOI: 10.1016/j.bbrc.2010.12.011

Genes

VAPB
VAPA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21144830-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Human VAPA and the yeast VAP Scs2p with an altered proline distribution can phenocopy amyotrophic lateral sclerosis-associated VAPB(P56S).PMID 21144830Read ↗

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