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Article

New VAPB deletion variant and exclusion of VAPB mutations in familial ALS.

Neurology - 1 Apr 2008

Landers J E, Leclerc A L, Shi L, Virkud A, Cho T, Maxwell M M, Henry A F, Polak M, Glass J D, Kwiatkowski T J, Al-Chalabi A, Shaw C E, Leigh P N, Rodriguez-Leyza I, McKenna-Yasek D, Sapp P C, Brown R H

Abstract excerpt

OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is a progressive, neurodegenerative disorder involving upper and lower motor neurons. The vesicle-associated membrane protein B (VAPB) gene has been genetically linked to ALS in several large Brazilian families in which the disorder is caused by a pr...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18322265
DOI: 10.1212/01.wnl.0000289760.85237.4e

Genes

VAPB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18322265-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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