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Article

What factors determine the severity of hepatitis A-related acute liver failure?

Journal of viral hepatitis - 1 Jul 2011

Ajmera V, Xia G, Vaughan G, Forbi J C, Ganova-Raeva L M, Khudyakov Y, Opio C K, Taylor R, Restrepo R, Munoz S, Fontana R J, Lee W M

Abstract excerpt

The reason(s) that hepatitis A virus (HAV) infection may progress infrequently to acute liver failure are poorly understood. We examined host and viral factors in 29 consecutive adult patients with HAV-associated acute liver failure enrolled at 10 sites participating in the US ALF Study Group. Eighteen of twenty-four acute liver failure sera were PCR positive while six had no detectable virus. HAV genotype was...

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Identifiers

PMID: 21143345
DOI: 10.1111/j.1365-2893.2010.01410.x
PMCID: PMC4931904

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