Article
A candidate gene association study of alcohol consumption in young women.
Alcoholism, clinical and experimental research - 1 Mar 2011
Agrawal Arpana, Lynskey Michael T, Todorov Alexandre A, Schrage Andrew J, Littlefield Andrew K, Grant Julia D, Zhu Qin, Nelson Elliot C, Madden Pamela A F, Bucholz Kathleen K, Sher Kenneth J, Heath Andrew C
Abstract excerpt
BACKGROUND: Excessive alcohol consumption contributes to significant morbidity and mortality. Heritable influences contribute to 50% of the variation in alcohol consumption, suggesting the important role of genes. We used data on a previously defined alcohol consumption factor score in a sample of 827 young women to investigate association with 1,014 single-nucleotide polymorphisms in genes related to addiction....
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