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Article

IL-12 deficiency exacerbates inflammatory responses in UV-irradiated skin and skin tumors.

The Journal of investigative dermatology - 1 Nov 2008

Meeran Syed M, Punathil Thejass, Katiyar Santosh K

Abstract excerpt

IL-12 deficiency has been shown to promote photocarcinogenesis in mice. As UVB-induced inflammation is an important tumor-promoting event in the development of skin tumors, we determined the effects of IL-12-deficiency on UVB-induced inflammatory responses in mice. For this purpose, IL-12-knockou...

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Identifiers

PMID: 18509359
DOI: 10.1038/jid.2008.140
PMCID: PMC2574589

Genes

PCNA
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18509359-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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