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Article

Induction of multinucleation in oral squamous cell carcinoma tissue with mutated p53 surviving boron neutron capture therapy.

International journal of radiation biology - 1 Mar 2011

Fujita Yusei, Yamamoto Naofumi, Kato Itsuro, Iwai Soichi, Ono Koji, Sakurai Yoshinori, Ohnishi Ken, Ohnishi Takeo, Yura Yoshiaki

Abstract excerpt

PURPOSE: To clarify the role of p53 in boron neutron capture therapy (BNCT) for oral squamous cell carcinoma (SCC), the effect of BNCT on oral SCC xenografts with either wild-type or mutant-type p53 was examined. MATERIALS AND METHODS: Oral SCC cells expressing either wild-type (SAS/neo) or mutant-type p53 (SAS/mp53) were used to produce nude mouse tumours. Tumour-bearing mice received boronophenylalanine (BPA)...

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Identifiers

PMID: 21142704
DOI: 10.3109/09553002.2011.530336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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