Article
Genetic diversity of heat-labile toxin expressed by enterotoxigenic Escherichia coli strains isolated from humans.
Journal of bacteriology - 1 Apr 2008
Lasaro M A, Rodrigues J F, Mathias-Santos C, Guth B E C, Balan A, Sbrogio-Almeida M E, Ferreira L C S
Abstract excerpt
The natural diversity of the elt operons, encoding the heat-labile toxin LT-I (LT), carried by enterotoxigenic Escherichia coli (ETEC) strains isolated from humans was investigated. For many years, LT was supposed to be represented by a rather conserved toxin, and one derivative, produced by the reference H10407 strain, was intensively studied either as a virulence factor or as a vaccine adjuvant. Amplicons...
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